What is Glutathione? What are the Benefits of Glutathione? What is glutathione? Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver. It is essential because it Glutathione detoxifies your liver, protects your mitochondria, drives down inflammation, and handles about half of your body's antioxidant defense on its own. To push those benefits further, most people assume they need Glutathione mediated biotransformation in the liver modulates nanoparticle transport Nature Nanotechnology