Pigmented Lesions of the Oral Mucosa Pocket Dentistry This is a picosecond laser treatment of labial melanotic macules on the gingiva. Note the green flashes of the 532 nm laser as well as the immediate tissue whitening of the treated area. This Pigmented lesions of the oral mucosa and perioral : Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, & Endodontics Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review