A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Combination of Cysteine and Glutathione Prevents Ethanol Induced Hangover and Liver Damage by Modulation of Nrf2 Signaling in HepG2 Cells and Mice Glutathione IV Liver Detox for Rapid Liver Repair and Cleansing Frontiers Glutathione deficiency in the pathogenesis of SARS CoV 2 infection and its effects upon the host immune response in severe COVID 19 disease